cancer incidence and trend analysis in shahroud, iran, 2000 – 2010

background:  cancer is the third leading cause of death in iran, and its trend is increasing in recent years. national reports state that cancer registries in shahroud district had 204% coverage in 2008. this study investigated cancer situation in shahroud with complete details between 2000–2010. methods: data was obtained from national cancer registry software and analyzed after removing the repeated records. world standard population and direct standardization method was used to calculate age standardized incidence rates (asrs). annual percentage changes calculated using jointpoint software and poisson regression model was performed to calculate cancer incidence trends. results: a total of 2240 cancer cases were identified, 1234 (55.1%) in man and 1006 (44.9%) in woman. the mean age was 61.6 years (confidence interval, ci 95%: 60.9– 62.3). asrs of total cancers was 95.4 (ci 95%: 89.2–101.6) per 100,000; this rate was 114.8 (ci 95%: 107.9–121.6) for men and 105.2 (ci 95%: 100.6 –109.8) for women. the average annual increase in asr was 12.4%, which could not be attributed only to improve reporting. gastric cancer is the most common cancer in men, and breast cancer is most common in women. conclusion: cancer incidence rate has increased significantly in shahroud in recent years. a portion of this increase can be attributed to increased incidence of cancers, especially cancers of colorectal, gastric, breast, and skin. please cite this article as: fateh m, emamian mh. cancer incidence and trend analysis in shahroud, iran, 2000 – 2010. iran j cancer prev. 2013; 6(2):85-94. references 1. world health organization. fact sheet n°297; available from: http://www.who.int/mediacentre/factsheets/fs297/en/index.html. accessed september 10, 2012. 2. boyle p, levin b. world cancer report 2008. lyon, france: world health organization, international agency for research on cancer; 2008. 3. center for disease control. national cancer registration report, 2008. tehran: ministry of health and medical education; 2012. 4. doll r, payne p, waterhouse j. cancer incidence in five continents: a technical report. berlin, springer-verlag; 1966. 5. joinpoint regression program, version 3.5.4 - august 2012; statistical methodology and applications branch and data modeling branch, surveillance research program  national cancer institute. available from: http://surveillance.cancer.gov/joinpoint/. accessed september 10, 2012. 6. center for disease control. national cancer registration report, 2003. tehran: ministry of health and medical education; 2005. 7. center for disease control. national cancer registration report, 2004. tehran: ministry of health and medical education; 2006. 8. center for disease control. national cancer registration report, 2005. tehran: ministry of health and medical education; 2007. 9. center for disease control. national cancer registration report, 2006. tehran: ministry of health and medical education; 2008. 10. center for disease control. national cancer registration report, 2007. tehran: ministry of health and medical education; 2009. 11. esmail nasab n, moradi g, zareie m, ghaderi e, gheytasi b. survey of epidemilogic status and incidence rates of cancers in the patients above 15 years old in kurdistan province. scientific journal of kurdistan university of medical sciences. 2007; 11(4):18-25. (full text is in persian). 12. hemati k, mohagheghi ma, mousavi jarahi a, khabazkhoob m. cancer incidence in ilam. scientific journal of ilam university of medical sciences. 2009; 17(3):24-32. (full text is in persian). 13. zeinalzadeh ah, kousha a, abdullahi l, golzari mn, javaheri j. pattern of age distribution of different cancers in east azerbaijan province, iran. journal of kerman university of medical sciences. 2012; 19(3):308-16. (full text is in persian). 14. mohaghegh f, hamta a, shariatzadeh sma. the study of cancer incidence and cancer registration in markazi province between 2001-2006 and comparison with national statistics, iran. journal of arak university of medical sciences. 2008; 11(2):84-93. (full text is in persian). 15. najafi f, jafari r, mozaffari hr, laghaei z. trend in lung cancer incidence in kermanshah province -iran, 1997-2007. behbood. 2010; 14(4):342-8. (full text is in persian). 16. najafi f, mozaffari hr, karami m, izadi b, tavvafzadeh r, pasdar y. trends in incidence of gastrointestinal tract cancers in western iran, 1993-2007. iran red crescent med j. 2011; 13:805-10. 17. roshandel g, sadjadi a, aarabi m, keshtkar a, sedaghat sm, nouraie sm, et al. cancer incidence in golestan province: report of an ongoing population-based cancer registry in iran between 2004 and 2008. arch iran med. 2012; 15(4):196-200. 18. thrift ap, whiteman dc. the incidence of esophageal adenocarcinoma continues to rise: analysis of period and birth cohort effects on recent trends. ann oncol. 2012; 23(12):3155-62. 19. sadjadi a, marjani h, semnani s, nasseri-moghaddam s. esophageal cancer in iran: a review. middle east j cancer. 2010; 1(1):5-14. 20. babai m, mousavi s, malek m, danaie n, jandaghi j, tousi j, et al. survey of cancer incidence during a 5-year (1998-2002) period in semnan province. koomesh. 2005; 6(3):237-44. (full text is in persian). 21. ferlay j, shin h, bray f, forman d, mathers c, parkin d. globocan 2008 v2.0, cancer incidence and mortality worldwide: iarc cancerbase no. 10 [internet]. lyon, france: international agency for research on cancer; 2010. available from: http://globocan.iarc.fr. accessed september 12, 2012. 22. shin mh, oh hk, ahn yo. ten year trend of cancer incidence in seoul, korea: 1993-2002. j prev med public health. 2008; 41(2):92-9. 23. rajaiefard a, moghimi b, tabatabaie sh, safaie a, tabeie sz. epidemiological and clinical features of gastric cancer: descriptive study of cancer registry cases of fars province (2001-2006). iranian south medical journal. 2011; 14(2):114-21. (full text is in persian).